(2-thiapropyl)magnesium chloride - Names and Identifiers
(2-thiapropyl)magnesium chloride - Physico-chemical Properties
(2-thiapropyl)magnesium chloride - Introduction
(2-thiapropyl)magnesium chloride is an organomagnesium compound with the chemical formula C3H5ClMgS. The following is a description of its nature, use, preparation and safety information:
1. nature:
(2-thiapropyl)magnesium chloride is a colorless or pale yellow liquid with an oil-like odor. It can react with water and moisture in the air to produce hydrogen chloride gas and hydrogen sulfide gas. The compound is soluble in organic solvents such as diethyl ether and dimethylformamide.
2. use:
(2-thiapropyl)magnesium chloride can be used as an important reagent in organic synthesis, mainly for the formation of carbon-carbon bonds. It can react with aldehydes, ketones, esters and other compounds to generate the corresponding carbon-carbon bond products. In addition, the compound can also be used to prepare other organic magnesium reagents.
3. preparation method:
The preparation of (2-thiapropyl)magnesium chloride is generally carried out by the Grenard reagent reaction. First, 2-thiipropanol is reacted with magnesium metal in an inert solvent, such as dry ether, to obtain a solution of Grenade reagent (2-thipropyl) magnesium. Then, hydrogen chloride (or ferrous chloride) is added to continue the reaction to give the final product (2-thiapropyl)magnesium chloride.
4. Safety Information:
(2-thiapropyl)magnesium chloride is an organic magnesium compound with certain risks. Appropriate protective equipment such as gloves, goggles and laboratory coats should be worn during operation. Avoid contact with skin and inhalation of its vapors. The compound should be stored in a sealed container and protected from contact with oxygen and moisture. In the process of handling, the relevant safety operation procedures shall be strictly followed to ensure the safety of personnel and environment.
Last Update:2024-04-10 22:29:15